Endocrine Abstracts

Background: In spite of being the most frequent genetic form of male hypogonadism, Klinefelter’s syndrome is not so rarely undiagnosed until adulthood. As the severity of manifestations in Klinefelter’s syndrome is proportional to the number of additional X chromosomes, they seem less severe and aparent in its classic form, with a 47,XXY karyotype than in cases of this syndrome with mosaicism and other variants.Case report: A 25-year-old male w...

Background: Adrenal incidentalomas (AI) represent incidentaly discovered adrenal mases, without simptoms or signs suggestive of adrenal pathology, at the time of visualization. It is well-known that overt or subclinical hypercorticism, as well as metabolic syndrome (MetS) harbour increased CV risk.There is still persisting debate on eventual cause-effect relationship of AI with metabolic syndrome MetS or probability of simply more frequent occurance of AI among these patients....

Introduction: The role of metformin in PCOS is very well known and several studies reported effects of thiazolidinediones and SGLT2 inhibitors on metabolic parametars in these patients.Objective: The aim of this study was to compare the effects of metformin, pioglitazone and empagliflozin treatment on metabolic control, hormonal imbalance, weight loss and ovulations in obese patients with PCOS and prediabetes.Methods: BMI, waist ci...